How Did It Go

On day 28 September 2018 Pharmapack Symposium had the first event of ever in Thailand. Why we chose Thailand? Thai pharmaceutical market is large and growing fast and supported by a strong long term Government funding plan. The market is dominated by generic drugs in terms of volume. The new medicines are coming up and showing good efficacy over the old generics, yet the country still needs to import a lot of products. Nevertheless, the local industry is investing in new technology entering the field of injectables as stated by Mr. 'Totsapon Santitewagun president of ISPE Thailand, he also refers that in a long term view he expects the market to contract in total number of companies, but expand in total value. That’s why there will be an increased need for expertise in the focus areas. Fulfill this expertise need is one of the reason why Pharmapack symposium came in Bangkok this year. The full day conference has been chaired by Mr. Gabriele Peron (International Commission on Glass Steering committee member) together with Mr. Totsapon Santitewagun

The first regulatory session dedicated to the key aspect of data integrity management trends done by Mr. Coviello and the most recent update on the technical requirements of Type I Glass for Pharmaceutical Containers as outcome of ICG Technical Commission 12 delivered by Dr. Daniele Zuccato secretary of the chapter.

More than 80 attendees representatives of Thailand pharmaceutical industry including some from nearby countries joint this unique event dedicate to the “Development of Pharma Manufacturing: Technological Solutions and Services from Early Phase to Industrialization.

Primary packaging plays a key role in assuring the safety of drugs and this has been deeply analyzed by NEG speaker Mr. Mohd Nazri who describes the process and the criteria for producing glass tubing for pharmaceuticals. Martina Largoni (Ompi) show the most recent improvements and the latest application on manufacturing process based on tubular glass explaining how to reduce TCO keeping high quality levels in bulk and sterile formats.

West talked about the recent legislation about safety and the need on the pharma industry to deliver safety systems on prefillable syringes. The difference between active and passive systems has been illustrated, explaining the key advantages in terms of usability by patient’s perspective.

 The session dedicated to manufactory trends was open by Mr. Alain Kupferman who talked about how flexibility paradigm is changing the way of design manufacturing plants and process. He stated that flexibility is a must but it has to be based on rational decisions having clear in mind limits and advantages. Starting from this point Mr. Christopher Sweeney (Kalbio) from Indonesia describes a real case of implementing a flexible process based on the first Isolator installed its country. Slavik Kristian from Optima describes the fill&finish recent developments with a  special attention on the combi technologies that are nowadays used to fill vial, cartridges and syringes directly in Nest and Tubs. The most recent trends in drug delivery systems based on cartridges or pfs were described by Tobias Nemeth from Ypsomed. He highlighted also which critical aspects need to be take in consideration since the early phase of design of a pen or an autoinjector system.

The last presentation was delivered by Gaetano Baccinelli - Optrel inspection systems who explained how to reduce false rejection rate using new technologies able to detect particles and defects on filled glass containers. In the final part of the conference all speakers were asked to attend a question and answer session where all attendees had the chance to clarify their doubts.

All presentations are available for Pharmapack symposium registered members. www.pharmapack-symposium.org