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The protection of people against infectious deceases is one of the big achievements in medical science in public health. Vaccines contribute to a decrease of incidents of infectious deceases around the world. The vaccine market is a relatively small but interesting market.

At the moment only 2% of the pharmaceutical market is related to vaccines, but the vaccine market is rapidly growing each year.

The current vaccine market can be characterized as a monopsony. Due to different merges in the recent years, there are only few big vaccine manufacturers in the market.

There is also a limited amount of substantial buyers. Usually governments are responsible for the procurement of vaccines, to cover their National Immunization Program.

However, also different international organizations play an important role in the procurement and distribution of vaccines worldwide.

Research & Development, innovation, quality control, GMP, overhead, staff, and material costs are costly and cover a substantial part of the final price per dose. Different trends show that the demand for safe and affordable vaccines will stay high and even increase.

Emerging countries play a critical role in the availability in the availability of these safe and affordable vaccines.

The presentation will give an overview about the historical basis of the syringe developments and highlight the requirements of different therapeutic classes.

Current market size and future developments will be presented as well as technical characteristics and requirements on drug delivery systems for individual therapeutic classes will be discussed.

Helvoet Pharma designs, produces and markets primary packaging components for pharma, diagnostic and medical devices striving to meet and even anticipate the ever increasing quality requirements of the Healthcare market especially in the PFS product range.

After a brief summary of our standard solutions to supply the market with state of the art components in the various market segments served, we focus on our existing products range for the PFS which has been recently completed with product designs and rubber formulation compatible with the most sophisticated drugs and solvents.

OCP coated plungers are described as well as rigid needle shields.Packaging in dedicated containers equipped with RTP ports is presented both in steam sterilizable and irradiation resistant bags.

With the advances of the pharmaceutical industry in challenging therapeutic areas (biotechs, oncology, vaccines, emergency drugs, cosmetic surgery and imaging) and the increasing trend for user-friendly and safer self-administration systems, prefilled syringes offer the preferred solution.

Their advantages are many: Immediate Effect, Safety, Cost Effectiveness, Product Life-Cycle Management. Nuova Ompi provides products and services that consistently evolve to meet the needs of the pharmaceutical industry, a specific and complex world that is continually seeking new solutions to meet global demands. EZ-fill™ is the ready-to-fill range of products provided by Ompi consistently with its long tradition of excellence.

The planning and execution of the manufacture of EZ-fill™ has been achieved by harnessing the synergy within the Nuova Ompi of long term experience in forming glass containers of the highest quality using the latest machinery for forming and inspecting syringe barrels to provide a synchronized solution.

Equally important is the establishment of a partnership with key suppliers and consultants from the pharmaceutical industry to design and build a new manufacturing facility to meet the growing needs of the pharmaceutical industry. EZ-fill™ offers the industry a new choice for glass pre-fillable syringes.

As inspection of ampoules, vials, cartridges and syringes is a crucial process for producers of pharmaceutical containers, Optrel develops systems designed to contribute to zero-defect quality for packed products. This presentation aims to treat the vision systems enabled to perform:

- Cosmetic inspect to control the integrity of the vials body, closure and the correct shape of the tip for ampoules.
- Contents of containers to detect the presence of particles contamination inside the product and the correct filling volume.
- inspection technique using our Linear scan and CCD cameras at various resolutions
- Inspection of freeze dried products