The benefits of Future–oriented Technologies for machine manufacture to cover and control the particles generation during filling& finish in room / Isolator. The Advantages of Virtual Applications
The pharmaceutical demands on machine manufacturers are steadily increasing. In the recent past, clean room classifications (RABS / isolators) and sterilization processes (UV / H2O2 / Plasma / e-beam) were the main focus.
Today dosing systems (rotary piston pump, time pressure, peristaltic pump) and stoppering are of great importance. Another trend of prime importance is the demand for automatic and 100% IPC.
Nested syringe machines must thereby provide a wide variety of performance options. Established syringe manufacturers are now offering nested cartridges and vials. Machine manufacturers need to act on such trends with sophisticated and flexible solutions.
All these objects are supplied pre-sterilized in trays. Multi use filling machines for ready-to-use components are the new trend in the pharma industry.
Today smaller batch size and higher value products are used compared to previous larger batch sizes.
The big challenge when developing a syringe processing line is the handling of different objects such as syringes, vials and cartridges on a single machine.
Optima pharma has realized the demands and has established a high flexibility to process ready-to-use components on one machine (Multi use filling machines).
In order to successfully construct the MultiUse Filler and to secure the machine concept, simulation of airflow conditions (virtual application) were used. Through this, the high development costs were saved.
The improved collection of data and targeted analysis increasingly helps improve the technical developments in the area of sterile rooms and isolators in which the airflow plays a key role.
The high level of complexity and dynamics of these processes alleviates the predictions of the airflow in such highly complex MultiUse fillers.
Weaknesses in design or problematic areas can be found early on due to the visual depiction of the airflow. The future lies in the virtual representation of machines within this industry.